4-(trifluoromethoxy)phenyl chlorothioformate - Names and Identifiers
4-(trifluoromethoxy)phenyl chlorothioformate - Physico-chemical Properties
Molecular Formula | C8H4ClF3O2S
|
Molar Mass | 256.63 |
Density | 1.507±0.06 g/cm3(Predicted) |
Boling Point | 96 °C(Press: 11 Torr) |
4-(trifluoromethoxy)phenyl chlorothioformate - Introduction
4-(Trifluoromethoxy) phenylchlorosulfuryl fluoride (4-(trifluoromethoxy)phenyl chlorothioformate) is a chemical substance with the following properties:
-Appearance: A colorless to pale yellow liquid
-Molecular formula: C8H4ClF3O2S
-Molecular weight: 274.63g/mol
-Melting point: below -50 ℃
-boiling point: 161-165 ℃
-Density: 1.544 g/mL at 25 ℃
-Solubility: Soluble in organic solvents such as ether and chloroform
4-(trifluoromethoxy) phenyl chlorothionyl fluoride main uses include the following aspects:
-As a reagent in organic synthesis: In organic synthesis reactions, it is often used as an acylation reagent to introduce chlorosulfonyl groups.
-Used in drug and pesticide research: This compound is an important intermediate that can be used to synthesize derivatives of drugs and pesticide molecules.
-Used in material science research: Due to its special structure, it can be used to prepare optical functional materials, biologically active compounds, etc.
Method for preparing 4-(trifluoromethoxy) phenyl chlorothionyl fluoride:
A commonly used preparation method is to react 4-(trifluoromethoxy) phenyl sodium sulfate with chlorocarbonyl fluoride to generate the target product.
When using or handling 4-(trifluoromethoxy) phenylchlorosulfuryl fluoride, the following safety information should be noted:
-The compound is irritating and should avoid contact with skin, eyes and respiratory tract. Wear protective gloves, glasses and masks during operation.
-During use, ensure adequate ventilation and avoid contact with fire sources.
-Need to be stored in a closed container, avoid light and humid environment.
-When disposing of waste, local regulations should be observed to avoid pollution to the environment.
-In case of inadvertent contact, rinse with plenty of water and seek medical advice.
Last Update:2024-04-10 22:41:03